Search on: CYCLIC AMP RECEPTOR PROTEIN 
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Descriptor English:   Cyclic AMP Receptor Protein 
Descriptor Spanish:   Proteína Receptora de AMP Cíclico 
Descriptor Portuguese:   Proteína Receptora de AMP Cíclico 
Synonyms English:   Catabolite Gene Activator Proteins
Catabolic Gene Activators
Catabolite Activator Protein
Catabolite Gene Activator Protein  
Tree Number:   D12.776.930.165
Definition English:   A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES. 
History Note English:   94; was CATABOLITE GENE ACTIVATOR PROTEINS 1988-93; CYCLIC AMP RECEPTOR PROTEIN was see CATABOLITE GENE ACTIVATOR PROTEIN 1990-93; CATABOLITE GENE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLITE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLIC GENE ACTIVATORS was see RECEPTORS, CYCLIC AMP 1977-87 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   31804 
Unique Identifier:   D002373 

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